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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRAK1
All Species:
11.82
Human Site:
S451
Identified Species:
28.89
UniProt:
P51617
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51617
NP_001020413.1
712
76537
S451
E
A
G
V
A
L
R
S
T
Q
S
T
L
Q
A
Chimpanzee
Pan troglodytes
XP_521332
850
89683
S592
E
A
G
V
A
L
R
S
T
Q
S
T
L
H
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549367
722
76996
S452
E
A
G
V
T
L
R
S
T
Q
S
T
L
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q62406
710
77251
S451
E
A
G
V
T
L
K
S
T
Q
P
T
L
W
V
Rat
Rattus norvegicus
Q4QQS0
624
69218
L405
I
F
S
C
G
I
V
L
A
E
V
L
T
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508862
872
94244
R562
E
A
D
E
P
Q
K
R
N
W
P
S
T
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697688
686
76453
R440
C
K
K
H
L
D
R
R
L
T
A
K
D
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002312803
404
44281
G185
S
L
E
N
H
L
F
G
R
G
S
A
V
Q
P
Maize
Zea mays
NP_001132095
412
44547
K193
V
Y
E
F
M
P
N
K
S
L
D
D
H
L
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q06548
410
45501
F191
G
A
A
K
G
L
A
F
L
H
S
S
E
T
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
N.A.
83
N.A.
81
27.6
N.A.
49.4
N.A.
N.A.
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
78.9
N.A.
87.8
N.A.
85.2
44.9
N.A.
59
N.A.
N.A.
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
66.6
0
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
73.3
13.3
N.A.
26.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.8
25.8
N.A.
22.8
N.A.
N.A.
Protein Similarity:
33
36.2
N.A.
35.3
N.A.
N.A.
P-Site Identity:
20
0
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
6.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
10
0
20
0
10
0
10
0
10
10
0
10
30
% A
% Cys:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
0
0
0
10
10
10
0
0
% D
% Glu:
50
0
20
10
0
0
0
0
0
10
0
0
10
0
0
% E
% Phe:
0
10
0
10
0
0
10
10
0
0
0
0
0
0
10
% F
% Gly:
10
0
40
0
20
0
0
10
0
10
0
0
0
10
10
% G
% His:
0
0
0
10
10
0
0
0
0
10
0
0
10
10
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
10
10
0
0
20
10
0
0
0
10
0
0
0
% K
% Leu:
0
10
0
0
10
60
0
10
20
10
0
10
40
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
0
0
0
0
20
0
0
0
20
% P
% Gln:
0
0
0
0
0
10
0
0
0
40
0
0
0
30
0
% Q
% Arg:
0
0
0
0
0
0
40
20
10
0
0
0
0
0
10
% R
% Ser:
10
0
10
0
0
0
0
40
10
0
50
20
0
10
0
% S
% Thr:
0
0
0
0
20
0
0
0
40
10
0
40
20
10
0
% T
% Val:
10
0
0
40
0
0
10
0
0
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _